Multifocal Transcranial Current Stimulation for Cognitive and Motor Dysfunction in Dementia

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Healthy Volunteers: f
View:

⁃ Participants (Ps)

• willing and capable to give informed consent for the participation in the study after it has been thoroughly explained

• able and willing to comply with all study requirements

• an informed consent form was signed

• able to read, write, and communicate in English

• able to identify an eligible administrator to participate with them in the study

⁃ Caregiver/Administrators (As)

• at least 21 years of age

• able to read, write, and communicate in English

• self-reported computer proficiency and willingness to learn how to use tES as defined by yes answers to the questions Do you feel comfortable using a computer? and Are you willing to be the primary caregiver for a participant and learn how to administer tES?

• stated availability during weekdays throughout the study period to administer tES to the Ps

Locations
United States
Massachusetts
Hinda and Arthur Marcus Institute for Aging Research
RECRUITING
Boston
Contact Information
Primary
HomeStim Study
homestim@hsl.harvard.edu
617-971-5416
Time Frame
Start Date: 2023-01-24
Estimated Completion Date: 2027-08-31
Participants
Target number of participants: 144
Treatments
Experimental: tACS(AG) + tDCS(PFC) combo active
Participants (Ps) will undergo 20min of daily home-based tACS active + tDCS active intervention over the left angular gyrus and prefrontal cortex for 4 weeks by their trained caregiver/administrators (As).
Active_comparator: tACS(AG) active + tDCS(PFC) sham
Participants (Ps) will undergo 20min of daily home-based tACS active + tDCS sham intervention over the left angular gyrus and prefrontal cortex for 4 weeks by their trained caregiver/administrators (As).
Active_comparator: tACS(AG) sham + tDCS(PFC) active
Participants (Ps) will undergo 20min of daily home-based tACS sham + tDCS active intervention over the left angular gyrus and prefrontal cortex for 4 weeks by their trained caregiver/administrators (As).
Sham_comparator: tACS(AG) sham + tDCS(PFC) sham
Participants (Ps) will undergo 20min of daily home-based tACS sham + tDCS sham intervention over the left angular gyrus and prefrontal cortex for 4 weeks by their trained caregiver/administrators (As).
Sponsors
Leads: Hebrew SeniorLife
Collaborators: BrightFocus Foundation, National Institute on Aging (NIA)

This content was sourced from clinicaltrials.gov